Dobutamine is a Beta-1 agonist.

Mechanism of Action: Dobutamine stimulates Beta-1 receptors to increase heart rate, force of contraction, and conduction velocity.

Indications: Dobutamine is used to treat cardiogenic shock and severe heart failure to increase contractility and cardiac output.

Nursing Considerations: In IV administration, dilute concentration before administering. Continuously monitor electrocardiogram (ECG), blood pressure, cardiac output, and urine output during therapy.

Side Effects/Adverse Effects: Adverse effects of Beta-1 agonists include marked increase in heart rate and blood pressure. Individuals should promptly report difficulty breathing, angina, palpitations, or dizziness.

Patient Teaching & Education: The patient should be instructed to inform the nurse immediately if they notice chest pain, shortness of breath, or numbness or tingling in the extremities.[1]

Now let’s take a closer look at the dobutamine medication grid in Table 4.11.[2]

Table 4.11 Dobutamine Medication Grid

Class/Subclass
Prototype/Generic
Administration Considerations
Therapeutic Effects
Side/Adverse Effects
Beta-1 Agonist dobutamine Continuously monitor ECG, blood pressure, cardiac output, and urine output during therapy Increases heart rate, force of heart contraction, and speed of conduction between SA to AV nodes Marked increase in heart rate and blood pressure

Report all adverse reactions promptly, especially labored breathing, angina, palpitations, and dizziness

 


  1. uCentral from Unbound Medicine. https://www.unboundmedicine.com/ucentral
  2. This work is a derivative of DailyMed by U.S. National Library of Medicine in the Public Domain.

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