Glossary of Terms
- adipocytes
-
mature cells found in adipose (fat) tissue - filled with a large storage sac of lipid. The lipid in these cells does not stain well with H&E staining, so the cells appear empty.
- agranulocytes
-
without prominent-staining cytoplasmic granules
- anucleate
-
without a nucleus
- apical
-
the exposed side of epithelial tissue
- aponeuroses
-
connective tissue connections between to muscle groups
- articular cartilage
-
cartilage that surrounds the articular surface of bones (surfaces where bone meets bone to form a joint). This cartilage decreases friction in movement and provides cushioning
- articulate
-
two bones connecting to form a joint
- Avascular
-
without blood vessels
- Axon
-
axon hillock of the cell body narrows to become the axon, which transmits electrical signals to the axon terminus to communicate with other cells
- basal
-
the anchored side of epithelial tissue
- basement membrane
-
a thin layer of connective tissue that anchors the cells of epithelial tissues to the deeper structures of our body
- biconcave
-
narrow in the center and thicker on the edges, RBC's are biconcave or shaped like a donut (if the icing touched in the center)
- bone matrix
-
extracellular matrix containing collagen, calcium-binding proteins, calcium and phosphate depositions
- branched
-
branched cells will resemble the letter Y. A branched cell may connect to one cell on one end, but two cells on the other end.
- canaliculi
-
meaning "tiny canal"
- Cell body
-
contains nucleus and organelles and serves as the biosynthetic center of the cell (synthesizes biological molecules)
- central canal
-
running the length of the osteon, containing blood vessels and nerves
- chondrocytes
-
mature cells found in cartilage that monitor and maintain the cartilage extracellular matrix
- chromatin
-
DNA wrapped around histone proteins
- chromosomes
-
tightly coiled, condensed DNA wrapped around proteins
- cilia
-
surface appendages found in some epithelial cells that move in a rhythmic manner to move mucous across the apical suface of the tissue
- cleavage furrows
-
pinching or narrowing of the plasma membrane during cytokinesis
- Collagen
-
Collagen is a fibrous protein that has many structural types
- Columnar
-
a tall, rectangular cell with an egg-shaped nucleus
- concurrent
-
occurring with or simultaneous
- cross section
-
a transverse section, cutting perpendicular to the length of a structure. If cutting a tubular structure, a cross section would produce a ring of tissue
- Cuboidal
-
a cube-shaped cell with a round nucleus
- cutaneous plexus
-
a network of blood vessels in the skin
- Cytokinesis
-
occurring with mitosis, cytokinesis is the division of the cytoplasm resulting in two new cells
- deep
-
closer to the center, away from the surface
- Dendrites
-
receive stimuli (signals/information) from environment or other neurons, which are conducted to the axon
- dermis
-
the deepest region of the skin (underlying the epidermis), consisting of two layers: the papillary layer is areolar connective tissue and the reticular layer is dense irregular connective tissue
- desmosomes
-
cell junction that allows tissues to resist pulling and tearing
- diaphysis
-
a long central shaft of a long bone, containing the medullary cavity surrounded by compact bone
- eccrine sweat glands
-
secrete watery sweat that assists in thermoregulation (homeostasis of body temperature) and additionally secrete some waste products and provide some protection against microorganisms
- Elastic fibers
-
provide elasticity to tissues - the ability to be pulled and recoil like a rubber band
- Embryonic origin
-
The embryo has three major layers - endoderm, mesoderm, ectoderm.
- endosteum
-
connective tissue membrane lining the internal surfaces of bone
- endothelium
-
the specialized simple squamous epithelium that lines the lumen of blood vessels
- epidermis
-
superficial region of the skin, -epi means above or upon (above/upon the dermis)
- epiglottis
-
located in the larynx (throat), moves to prevent food from entering the trachea (airway) during swallowing
- epiphysis
-
the end of a long bone, containing a core of spongy bone surrounded by an outer covering of compact bone
- erythrocytes
-
red blood cells, biconcave cells lacking a nucleus and organelles that contain ~250 million molecules of hemoglobin
- extracellular matrix
-
structural proteins and surrounding ground substance
- extracellular matrix (ECM)
-
the fluid, macromolecules, and minerals that surround cells in our tissues, specifically connective tissues
- fibroblasts
-
cell type found in connective tissue that actively produces the proteins in the extracellular matrix
- gap junctions
-
cell junction that allows passage of ions from the cytoplasm of one cell to the cytoplasm of the neighboring cell. The flow of ions allows cardiac muscle tissue to communicate electrically.
- Glial cells
-
cells that play an important role in supporting neurons and the nervous system
- goblet cells
-
uni-cellular mucous-producing gland found in epithelium
- granulocytes
-
contain prominent-staining cytoplasmic granules
- ground substance
-
consists of soluble proteins, nutrients, ions, waste products, dissolved gasses
- H&E
-
hematoxylin and eosin staining protocol
Hematoxylin - purple/blue, stains nucleic acids (basophilic) - highlights nucleus and rough ER (ribosomes have RNA)
Eosin - pink, stains proteins (acidophilic) - highlights connective tissue proteins (collagen), plasma membrane, cytoplasm - hair follicle receptor
-
nerve endings that wrap around the base of the hair follicle for sensation of touch
- homeostasis
-
a dynamic (constantly adjusting) state of equilibrium
- hypodermis
-
layer of connective tissue, primarily adipose tissue, located deep to the dermis
- innervated
-
having nerve endings for sensory or motor function
- intercalated discs
-
specialized cell-to-cell connections in cardiac muscle tissue containing gap junctions and desmosomes
- interphase
-
During Interphase the cell carries out normal functions, grows, and replicates its DNA
- interstitial fluid
-
the fluid in between our cells
- involuntary
-
under sub-concious control, occurs without you thinking about it.
- keratinized
-
containing keratin, a structural protein found in skin, hair, and nails
- lacunae
-
A gap, cavity, or depression. Osteocytes (bone) and chondrocytes (cartilage) are found within lacunae.
- lamellae
-
sheets or layers
- leukocytes
-
white blood cells, function in immune response
- longitudinal section
-
cut along the long axis of a tissue
- lumen
-
the interior of a tube-shaped organ, like a blood vessel, kidney tubule, or intestines
- lymphocytes
-
a type of lymphocyte (white blood cell) that is part of our adaptive immune system (i.e., B-cells and T-cells)
- macrophages
-
phagocytic cells that engulf (phagocytose) cellular debris or pathogens
- melanocytes
-
pigment (melanin)-producing cells in the epidermis
- mesenchyme
-
loosely arranged connective tissue in the embryo that originates from the mesoderm
- Mitosis
-
nuclear division that separates the replicated chromosomes resulting in two nuclei
- multinucleated
-
cell that contains many nuclei
- Neurons
-
excitable cells that can receive and send electrical signals
- Nissl bodies
-
granular substance in neuron cell body caused by the staining pattern of the rough ER
- nucleated
-
containing a nucleus
- osteoblasts
-
immature bone cells that deposit new bone matrix
- osteocytes
-
mature cells in bone tissue that monitor and maintain the osseous tissue matrix
- osteogenic cells
-
stem cells in bone that can form osteoblasts and osteocytes
- osteons
-
the functional unit in compact bone, consisting of a central (Haversian) canal surrounded by concentric rings/layers of bone matrix called lamellae
- papillary layer
-
superficial layer of the dermis, made of areolar connective tissue
- periosteum
-
connective tissue membrane lining the external surfaces (non-articular) of bone
- peripherally-located
-
located to the outside (peripheral)
- perpendicular canals
-
running at right angles to the central canal, containing blood vessels and nerves
- plasma
-
the fluid in blood, containing dissolved solutes such as: proteins, blood gasses (CO2 and O2), hormones, nutrients, waste products
- platelets
-
fragments of a cell precursor (megakaryocytes) that function to stop bleeding of a damaged blood vessel
- Polarity
-
having two sides with different structural or functional characteristics.
- regeneration
-
the ability of a tissue to repair itself or to replace old cells with new cells
- regeneration capacity
-
the ability of a tissue to repair or replenish itself
- reticular fibers
-
a specialized type of collagen that forms branching networks (branches on a tree) instead of long, linear strands
- reticular layer
-
deep layer of the dermis, made of dense irregular connective tissue
- reticulocytes
-
mature cells found in reticular connective tissue, responsible for making reticular fibers
- scaffold
-
a structural support system
- sebaceous glands
-
secretes sebum (oil) that helps lubricate the skin and protect against microorganisms
- Simple
-
in epithelial tissues, a single layer of cells anchored to a basement membrane
- soma
-
means "body"
- Squamous
-
a scale-like, flattened cell with a disc-shaped nucleus
- Stratified
-
in epithelial tissues, a layer of two or more cells with the basal layer anchored to a basement membrane
- striated
-
perpendicular "striped" appearance of skeletal and cardiac muscle cells
- superficial
-
closer to the surface
- thermoregulation
-
regulation of body temperature
- trabeculae
-
plates/spikes of bone matrix found in spongy bone
- uninucleated
-
containing a single (1) nucleus
- vascularized
-
containing blood vessels
- voluntary
-
under concious control - you can actively choose to move your skeletal muscles
- white fish blastula
-
a blastula is a sphere of cells produced during the development of a white fish embryo by repeated mitosis and cleavage of a fertilized egg